{"id":32,"date":"2022-12-25T02:12:41","date_gmt":"2022-12-25T02:12:41","guid":{"rendered":"https:\/\/kurir-health.com\/?p=32"},"modified":"2023-05-25T11:47:02","modified_gmt":"2023-05-25T11:47:02","slug":"scientists-validate-effective-rehabilitation-and-recovery-of-human-donor-lungs-previously-considered-unsuitable-for-transplantation","status":"publish","type":"post","link":"https:\/\/kurir-health.com\/?p=32","title":{"rendered":"Scientists Validate Effective Rehabilitation and Recovery of Human Donor Lungs Previously Considered Unsuitable for Transplantation"},"content":{"rendered":"\n<p>The study shows that a new technique for regenerating donor lung tissue can increase the number organs available for lifesaving transplantation.<\/p>\n\n\n\n<p>According to a study recently published in&nbsp;<em>the Journal of Heart and Lung Transplantation<\/em>, a novel method of supporting and recovering donor lung outside the body has the potential to increase organs available for donation.<\/p>\n\n\n\n<p>Organ shortages are becoming more and more dire as thousands of people die each year while waiting for organ donors.&nbsp;Nearly 80% of donated lung tissue is too damaged to be transplanted, and this is often because the damage can be reversed.&nbsp;Rehab and recovery of unutilized organs is a promising way to reduce the organ shortage.<\/p>\n\n\n\n<p>The xenogeneic (cross-circulation) technique was developed by a cross-disciplinary team of surgeons, bioengineers, and scientists from Vanderbilt University and Stanford University. They also collaborated with New York-Presbyterian Hospital and State University of New York Downstate Medical Center. This involves temporarily attaching a donor human lung to a pig&#8217;s live organ to support and resuscitate it outside the body.<\/p>\n\n\n\n<p>The study validated and established a standard technique for performing cross-circulation of xenogeneic donor lungs.&nbsp;The study, &#8220;Technique for cross-circulation of human donor lungs in ex vivo&#8221;, is reported by&nbsp;<em>Journal of Heart and Lung Transplantation<\/em>. These results confirm the effectiveness of this technique for rehabilitation of human donor lungs that were initially considered unfit for transplantation.<\/p>\n\n\n\n<p>&#8220;Despite significant efforts over many decades, few approaches have been successful in expanding the number of organs that are available for transplant,&#8221; Dr. Matthew Bacchetta said, Surgical director of the Vanderbilt Respiratory Institute, at Vanderbilt University Medical Center, and lead author of this study.&nbsp;&#8220;Xenogeneic Cross-circulation is proving a robust method to ex vivo evaluate, and improve donor lungs.&#8221;<\/p>\n\n\n\n<p>Dr. John O&#8217;Neill is Chief Scientific Officer of Xylyx Bio, and co-author. He said that the technique gives donor organs a steady blood supply as well as multisystem physiological regulation \u2013 a powerful advantage in the field.&nbsp;&#8220;We are excited about the potential for this technique to increase the clinical utilization of organ donors and enable more lifesaving transplants for those in need,&#8221; said Dr. John O&#8217;Neill, Chief Scientific Officer at Xylyx Bio and co-author of the study.<\/p>\n\n\n\n<p>,<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"768\" height=\"313\" src=\"https:\/\/kurir-health.com\/wp-content\/uploads\/2023\/05\/image-31.png\" alt=\"\" class=\"wp-image-183\" srcset=\"https:\/\/kurir-health.com\/wp-content\/uploads\/2023\/05\/image-31.png 768w, https:\/\/kurir-health.com\/wp-content\/uploads\/2023\/05\/image-31-300x122.png 300w\" sizes=\"auto, (max-width: 768px) 100vw, 768px\" \/><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>The study shows that a new technique for regenerating donor lung tissue can increase the number organs available for lifesaving transplantation. According to a study recently published in&nbsp;the Journal of Heart and Lung Transplantation, a novel method of supporting and recovering donor lung outside the body has the potential to increase organs available for donation. [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":183,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7],"tags":[],"class_list":["post-32","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-cancer"],"_links":{"self":[{"href":"https:\/\/kurir-health.com\/index.php?rest_route=\/wp\/v2\/posts\/32","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/kurir-health.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/kurir-health.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/kurir-health.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/kurir-health.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=32"}],"version-history":[{"count":2,"href":"https:\/\/kurir-health.com\/index.php?rest_route=\/wp\/v2\/posts\/32\/revisions"}],"predecessor-version":[{"id":285,"href":"https:\/\/kurir-health.com\/index.php?rest_route=\/wp\/v2\/posts\/32\/revisions\/285"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/kurir-health.com\/index.php?rest_route=\/wp\/v2\/media\/183"}],"wp:attachment":[{"href":"https:\/\/kurir-health.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=32"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/kurir-health.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=32"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/kurir-health.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=32"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}