{"id":86,"date":"2022-03-06T00:18:56","date_gmt":"2022-03-06T00:18:56","guid":{"rendered":"https:\/\/kurir-health.com\/?p=86"},"modified":"2023-05-25T11:47:01","modified_gmt":"2023-05-25T11:47:01","slug":"safety-of-covid-19-vaccine-for-children-with-mis-c-appears-promising","status":"publish","type":"post","link":"https:\/\/kurir-health.com\/?p=86","title":{"rendered":"Safety of COVID-19 Vaccine for Children with MIS-C Appears Promising"},"content":{"rendered":"\n<p><em>A study supported by the NIH found no serious complications after rare immune conditions.<\/em><\/p>\n\n\n\n<p>In a study of children who had received a COVID-19 vaccine following the multisystem inflammatory disorder (MIS-C), there were no serious complications reported, including myocarditis and recurrence of MIS-C.&nbsp;Around half of participants had mild reactions such as fatigue and arm pain.&nbsp;The National Institutes of Health funded study shows that it&#8217;s safe to receive a vaccination after having MIS C.&nbsp;The results were published in&nbsp;<em>JAMA Network Open<\/em>.<\/p>\n\n\n\n<p>The study is the largest observational study of its kind that has examined COVID vaccination among this group. It helps to resolve a lingering issue about whether the COVID can increase health problems for young people who had MIS C, a rare but potentially fatal immune reaction that can happen after infection with SARS CoV-2, which causes COVID-19.<\/p>\n\n\n\n<p>According to the Centers for Disease Control and Prevention, MIS-C affects about 1 out of every 3,000-4,000 children and teens who have COVID-19.&nbsp;This condition can occur a few months after COVID and lead to organ failure.&nbsp;Myocarditis is a serious condition that can cause symptoms such as stomach pain, fever and rash.&nbsp;MIS-C is not known to have a specific cause, but medication can be used to reduce the inflammation which can harm organs.<\/p>\n\n\n\n<p>Families and healthcare professionals questioned if COVID vaccinations could cause more serious adverse reactions, such as a recurrence, in people with a history MIS-C. However, there were no data available on the topic.<\/p>\n\n\n\n<p>This cross-sectional analysis included 22 medical centres (21 in the United States, and 1 in Canada), who were participating in the NHLBI\u2019s Long-Term Results After the Multisystem Inflammatory Syndrome (MUSIC) Study.&nbsp;The study enrolled 385 patients with a prior MIS C who were eligible to receive COVID-19 vaccine.&nbsp;185 (48.1%) of this group received at least one dose.&nbsp;The median age of the participants was 12.2, and 73.5% of them were male.&nbsp;Participants were of different races &#8211; 24.3% Black, 31.9% Hispanic and 28.6% white.&nbsp;The median time between their MIS C diagnosis and their first vaccination dose was nine months.<\/p>\n\n\n\n<p>In 49% of those who had received a COVID vaccine after MIS-C there were mild side effects, mainly arm soreness or fatigue, which is similar to what the general public experiences.&nbsp;Researchers reported that there were no serious complications such as myocarditis, or recurrences of MIS C.<\/p>\n\n\n\n<p>Matthew D. Elias M.D. is a pediatric cardiologist and clinical assistant professor of Pediatrics at University of Pennsylvania in Philadelphia. He was the study&#8217;s co-leader.&nbsp;Audrey Dionne, M.D. is a pediatric cardiologist at Boston Children&#8217;s Hospital, and an assistant professor of pediatrics in Harvard Medical School Boston. She was also the co-leader of this study.&nbsp;Researchers have treated MIS-C in children throughout the pandemic.<\/p>\n\n\n\n<p>Dionne said that the findings support the CDC&#8217;s recommendations that patients with a MIS-C history receive a COVID vaccination at least 90 day after diagnosis, and that this is safe.<\/p>\n\n\n\n<p>The National Heart, Lung, and Blood Institute, part of NIH, said that &#8220;in light of the acute and the long-term effects of COVID-19, it is essential to continue development, testing, and the deployment of preventive and therapeutic agents both in at-risk group as well as general population.&#8221;<\/p>\n\n\n\n<p>CDC data shows that more than 9,000 Americans have been diagnosed with MIS C and 74 of them have died.&nbsp;According to other studies, the disease is on the decline.<\/p>\n\n\n\n<p>Dionne stated that the COVID vaccine has proven to be protective in preventing this rare condition from occurring.<\/p>\n\n\n\n<p>Researchers said that while many patients with MIS C make a complete clinical recovery, certain studies indicate chronic symptoms can persist after MIS C. This is why researchers believe long-term outcomes studies are beneficial.&nbsp;The MUSIC project is part of a collaborative research effort by the NIH called CARING for Children With COVID. It aims to understand the effects of COVID on children. Children account for 13% of all cases in the United States.<\/p>\n\n\n\n<p>The NHLBI&#8217;s MUSIC Study funded the research reported in this report. This study was supported by grants HL135680 HL135685 HL135683 HL135689 HL135646 HL135665 HL135678 HL135682 HL135666 HL135691 and HL068270.&nbsp;The study utilizes the research infrastructure of Pediatric Heart Network (a pediatric cardiology consortium funded by NHLBI) and HealthCore Inc., its data coordination center.<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"768\" height=\"426\" src=\"https:\/\/kurir-health.com\/wp-content\/uploads\/2023\/05\/image-23.png\" alt=\"\" class=\"wp-image-162\" srcset=\"https:\/\/kurir-health.com\/wp-content\/uploads\/2023\/05\/image-23.png 768w, https:\/\/kurir-health.com\/wp-content\/uploads\/2023\/05\/image-23-300x166.png 300w\" sizes=\"auto, (max-width: 768px) 100vw, 768px\" \/><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>A study supported by the NIH found no serious complications after rare immune conditions. In a study of children who had received a COVID-19 vaccine following the multisystem inflammatory disorder (MIS-C), there were no serious complications reported, including myocarditis and recurrence of MIS-C.&nbsp;Around half of participants had mild reactions such as fatigue and arm pain.&nbsp;The [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":162,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[6],"tags":[],"class_list":["post-86","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-infectious-diseases"],"_links":{"self":[{"href":"https:\/\/kurir-health.com\/index.php?rest_route=\/wp\/v2\/posts\/86","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/kurir-health.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/kurir-health.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/kurir-health.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/kurir-health.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=86"}],"version-history":[{"count":2,"href":"https:\/\/kurir-health.com\/index.php?rest_route=\/wp\/v2\/posts\/86\/revisions"}],"predecessor-version":[{"id":277,"href":"https:\/\/kurir-health.com\/index.php?rest_route=\/wp\/v2\/posts\/86\/revisions\/277"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/kurir-health.com\/index.php?rest_route=\/wp\/v2\/media\/162"}],"wp:attachment":[{"href":"https:\/\/kurir-health.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=86"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/kurir-health.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=86"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/kurir-health.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=86"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}